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Reviews of "LOW BIRTH WEIGHT AS A RISK FACTOR FOR SEVERE COVID-19 IN ADULTS"

Reviewers: Stephanie Eick, Naida Gaber (UCSF) | πŸ“™πŸ“™ ◻️◻️◻️ β€’ Anders Hviid (Statens Serum Institut) | πŸ“’πŸ“’πŸ“’β—»οΈβ—»οΈ

Published onDec 02, 2020
Reviews of "LOW BIRTH WEIGHT AS A RISK FACTOR FOR SEVERE COVID-19 IN ADULTS"
key-enterThis Pub is a Review of
LOW BIRTH WEIGHT AS A RISK FACTOR FOR SEVERE COVID-19 IN ADULTS
Description

The identification of factors predisposing to severe COVID-19 in young adults remains partially characterized. Low birth weight (LBW) alters cardiovascular and lung development and predisposes to adult disease. We hypothesized that LBW is a risk factor for severe COVID-19 in non-elderly subjects. We analyzed a prospective cohort of 397 patients (18-70y) with laboratory-confirmed SARS-CoV-2 infection attended in a tertiary hospital, where 15% required admission to Intensive Care Unit (ICU). Perinatal and current potentially predictive variables were obtained from all patients and LBW was defined as birth weight ≀2,500 g. Age (adjusted OR (aOR) 1.04 [1-1.07], P=0.012), male sex (aOR 3.39 [1.72-6.67], P<0.001), hypertension (aOR 3.37 [1.69-6.72], P=0.001), and LBW (aOR 3.61 [1.55-8.43], P=0.003) independently predicted admission to ICU. The area under the receiver-operating characteristics curve (AUC) of this model was 0.79 [95% CI, 0.74-0.85], with positive and negative predictive values of 29.1% and 97.6% respectively. Results were reproduced in an independent cohort, from a web-based survey in 1,822 subjects who self-reported laboratory-positive SARS-CoV-2 infection, where 46 patients (2.5%) needed ICU admission (AUC 0.74 [95% CI 0.68-0.81]). LBW seems to be an independent risk factor for severe COVID-19 in non-elderly adults and might improve the performance of risk stratification algorithms.

To read the original manuscript, click the link above.

Summary of Reviews: This study suggests that low birth weight (LBW) could be a risk factor for severe COVID-19. Reviewers found that the methods employed were not rigorous to support this conclusion, and there remains a more complex relationship between LBW and adverse pulmonary outcomes.

Reviewer 1 (Stephanie Eick,Β Naida Gaber) | πŸ“™πŸ“™ ◻️◻️◻️

Reviewer 2 (Anders Hviid) | πŸ“’πŸ“’πŸ“’ ◻️◻️

RR:C19 Strength of Evidence Scale Key

πŸ“• ◻️◻️◻️◻️ = Misleading

πŸ“™πŸ“™ ◻️◻️◻️ = Not Informative

πŸ“’πŸ“’πŸ“’ ◻️◻️ = Potentially Informative

πŸ“—πŸ“—πŸ“—πŸ“—β—»οΈ = Reliable

πŸ“˜πŸ“˜πŸ“˜πŸ“˜πŸ“˜ = Strong

To read the reviews, click the links below.Β 

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http://sgm.controlminero.gob.ec/web/vapecig/home/-/blogs/health-hazards-posed-by-new-tobacco

https://mapman.gabipd.org/web/anastassia/home/-/message_boards/message/222984

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https://www.contratacionbogota.gov.co/vi/web/vapefactory/home

https://www.contratacionbogota.gov.co/vi/web/vapefactory/home/-/blogs/advantages-and-disadvantages-of-the-pod-type-vape

https://www.contratacionbogota.gov.co/vi/web/vapefactory/home/-/blogs/recommended-pod-type-vape

https://www.contratacionbogota.gov.co/vi/web/vapefactory/home/-/blogs/what-vapde-devices-do-you-recommend

https://www.contratacionbogota.gov.co/vi/web/vapefactory/home/-/blogs/5-disposable-vapes-recommended

https://caxman.boc-group.eu/web/vapecig/home

https://caxman.boc-group.eu/web/vapecig/home/-/blogs/what-brands-are-recommended-for-vape-beginners-

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https://www.laonsw.net/web/vapecig

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https://www.kooymantracking.com/web/vapecig/home/-/blogs/which-electronic-cigarette-vape-is-better

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https://s100.ust21.kr/web/vapecig

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https://s100.ust21.kr/web/vapecig/home/-/blogs/which-electronic-cigarette-vape-is-better

https://sensornet.lepida.it/web/vapecig/home

https://sensornet.lepida.it/web/vapecig/home/-/blogs/which-electronic-vape-for-cigarettes-is-superior

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https://www.syracuseultimate.org/web/vapecig

https://www.syracuseultimate.org/web/vapecig/home/-/blogs/which-electronic-vape-for-cigarettes-is-superior

https://www.syracuseultimate.org/web/vapecig/home/-/blogs/what-brands-are-recommended-for-vape-beginners

https://www.ehu.eus/eu/web/miguelsanchezmazaskatedra/foro/-/message_boards/message/41903570

https://www.ehu.eus/eu/web/miguelsanchezmazaskatedra/foro/-/message_boards/message/41904114

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http://www.scientix.eu/es_ES/web/scientix-cop-4/topic-1/-/message_boards/message/1310427

http://www.scientix.eu/es_ES/web/scientix-cop-4/topic-1/-/message_boards/message/1310435

http://1to1.eun.org/web/acer/work-area/-/wiki/Main/What+is+the+recommended+vape+brands/pop_up

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https://liferay.enaikoon.de/web/vapecig

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http://www.tsv-unterthuerheim.de/web/vapecig/home

http://www.tsv-unterthuerheim.de/web/vapecig/home/-/blogs/how-long-does-a-disposable-vape-pen-la-1

http://www.tsv-unterthuerheim.de/web/vapecig/home/-/blogs/how-can-i-charge-a-disposable-vape-pen

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https://topgradeapp.com/zh/lesson/the-rise-of-disposable-vapes-a-convenient-solution-or-an-environmental-disaster

https://topgradeapp.com/zh/lesson/exploring-the-pros-and-cons-of-disposable-vapes

https://topgradeapp.com/zh/lesson/understanding-the-health-risks-of-disposable-vapes

https://boosty.to/vapelife/posts/0dc771b0-5994-49ab-a78a-5a149bcf4f5a

https://boosty.to/vapelife/posts/9916b93f-3857-42f4-9c36-4a359b273abb

https://boosty.to/vapelife

https://k12.instructure.com/eportfolios/295556

https://k12.instructure.com/courses/930642/pages/pod-type-vape-is-a-hot-item

https://k12.instructure.com/courses/930642/pages/where-can-i-purchase-pod-type-vape

https://uws-ce.instructure.com/eportfolios/14146

https://hhi.instructure.com/courses/29901/pages/how-do-you-use-a-pod-vape

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https://collab.phys.unsw.edu.au:4432/bin/view/Main/Vapefactory

https://collab.phys.unsw.edu.au:4432/bin/view/Main/Disposablevape

https://collab.phys.unsw.edu.au:4432/bin/view/Main/Podvape

https://collab.phys.unsw.edu.au:4432/bin/view/Main/Puffs

https://collab.phys.unsw.edu.au:4432/bin/view/Main/SkinCare

http://wiki.cs.hse.ru/%D0%A3%D1%87%D0%B0%D1%81%D1%82%D0%BD%D0%B8%D0%BA:Vape

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